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95 Buick Le Sabre Misfiring

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Hello everybody, as i am just now learning the art of working on computer cars, I really need your help. I am having an ignition problem with our Buick. I recently took her to a local parts changer who got her running once again when the crankshaft sensor went out. She has been bumping and misfiring since. She did a little before. I took her back and the shop claimed there was resistance in the #5 sparkplug wire and they changed the wire out. to no prevail, they accepted my money and when i took it back, they claimed it was the torque converter and gave me a card to a friend. Well i took it to a local transmission shop who gav eme the green light on the tranny and produced code PO 300. Haines marks this as multiple/random cylinder misfiring. Any idea of how to get her back. The problem does feel like the problem you have when wires are going bad, but we know it is not. What are your thoughts....Mike in Ocklawaha Florida posted by  buymeaboat

I got that code in my acura along with 301 302 303 304. Ended up being the plugs I used. I went through cap rotor coil, tested the wires with no luck. I changed the plugs as a last resort and it solved the problem.
Either way a misfire code is generally something electrical. Start with the simple solutions and check back with us. posted by  DBain

or vacuum leaks downstream of the throttle body, etc. posted by  tbaxleyjr